The Association between TNF-alpha Gene Polymorphisms
and Endometriosis in An Iranian Population
Tumor necrosis factor-alpha (
Materials and Methods
We recruited 150 women with endometriosis and 150 women without endometriosis in this case-control study and collected 4 ml of blood from all subjects. After DNA extraction, the polymorphisms were geno- typed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).
The allele frequency of
For the first time the association of the four polymorphisms in the promoter region of the