Association between The Number of Retrieved Mature Oocytes
and Insulin Resistance or Sensitivity in Infertile Women
Polycystic Ovary Syndrome
The objective of this study was to describe the association between luteinizing hormone (LH)/ follicle-stimulating hormone (FSH) ratio and demographic variables and maturation stage of oocytes in insulin- resistant and insulin-sensitive patients with polycystic ovary syndrome (PCOS) in comparison with control group.
Materials and Methods
In this case-control study, 60 patients with
LH/FSH ratio was significantly higher in PCOS-IR women compared to controls but not significantly dif- ferent from that of PCOS-IS group. PCOS-IR women had lower MII oocyte number compared with that of controls. According to multiple regression analysis, the number of previous assisted reproductive technology (ART) cycles was negatively associated with the number of MII oocytes.
Insulin resistance can be associated with reductions in MII oocyte number in patients with PCOS.