Past Issue

Volume 12, Number 1, Apr-Jun 2018, Pages: 88-90

Conservative Management of Ovarian Fibroma in A Case of Gorlin-Goltz Syndrome Comorbid with Endometriosis

Sepideh Khodaverdi, M.D, 1, Leila Nazari, M.D, 1, *, Abolfazl Mehdizadeh-Kashi, M.D, 1, Mansoureh Vahdat, M.D, 1, Samaneh Rokhgireh, M.D, 1, Ali Farbod, M.D, 2, Banafsheh Tajbakhsh, M.D, 1,
Endometriosis Research Center, Iran University of Medical Science, Tehran, Iran
Department of General Surgery, Rasool-Akram Hospital, Iran University of Medical Science, Tehran, Iran
*Corresponding Address: P.O.Box: 1445613131 Endometriosis and Gyneco- logical Disorder Research Center Iran University of Medical Science Tehran Iran


Ovarian fibromas are the most common benign solid ovarian tumors, which are often difficult to diagnose preoperatively. Ovarian fibromas, especially in bilateral cases, may be cases of Gorlin-Goltz syndrome (GGS), a rare autosomal dominant disorder with predisposition to basal cell carcinomas (BCCs) and other various benign and malignant tumors. This case report describes a 25 year-old female with GGS, bilateral ovarian fibroma, endometriosis and septated uterus, which was referred to the Gynecology Clinic of Rasoul-e-Akram Hospital in October 2016. This patient had facial asymmetry due to recurrent odontogenic keratocysts. In young cases of ovarian fibromas as reported here, conservative surgical management can preserve ovarian function and fertility. These patients must be followed up by a multidisciplinary team and submitted to periodic tests.