Pnm-30: Assessment of The Relationship between Embryo Quality after ICSI and IVF at The Second and Third Days after Fertilization with Mothers’ BMI
Obesity has become a major health problem across the world. In women, it is known to cause anovulation, sub-fecundity, increased risk of fetal anomalies and miscarriage rates. However, in women going for assisted reproduction the effects of obesity on egg quality, embryo quality, clinical pregnancy, live birth rates are controversial To assess the effect of women's body mass index (BMI) on the reproductive outcome of non-donor in vitro fertilization (IVF) and Intracytoplasmic sperm injection (ICSI).
Materials and methods
Retrospective study of medical records of 204 women undergoing non donor IVF and ICSI cycles in Laleh and Taleghani Hospitals. Body mass index was calculated according to the generally accepted formula Weight/Height2, where weight is in grams and height is in centimeters. The patients were divided into three classes: <25 normal body mass, 26 to 29.9 overweight, and >30 obese and we must attend to oocyte quality and PCO.
This study shows, increase in BMI lead to decrease in fertilization rate (P value=0.055) and increase or decrease in BMI don’t have any impression on embryo quality but in people haven’t male factor, the number of embryo type B in group with BMI>25 is seventy percent more than women with BMI≤25. Furthermore, reverse relationship is seen between embryo quality and male factor.
Increase in body mass index in women does not appear to have an adverse effect on IVF outcome. However, pre-conceptual counseling for obese women is a must as weight reduction helps in reducing pregnancy-related complications.