Past Issue

Volume 9, Supplement 1, Summer 2015 (Presented at 16th Congress on Reproductive Biomedicine and 10th Royan Nursing and Midwifery Seminar) Pages: 76-76

P-78: Endometriosis and Physical Exercises among Infertile Iranian Women


Background
Endometriosis, defined by overgrowth of endometrial implants outside the uterine cavity, is commonly found on the ovaries. The role of exercise in this disease is not well understood. Regular exercise appears to have protective effects against endometriosis that involve inflammatory processes since it induces elevate systemic levels of inflammatory cytokines production with antioxidant properties and anti-inflammatory and also acts by decreasing estrogen concentrations. Evidence has suggested that the symptoms associated with endometriosis result from a local inflammatory peritoneal reaction caused by ectopic endometrial tissue. Thus, the purpose of this study is to assess the correlation between physical exercise and risk of an endometriosis diagnosis in infertile women.
Materials and methods
A case- control study in infertility Institute, Iran between 2014 and 2015. There were 150 infertile women with endometriosis (cases) and 150 infertile women a normal pelvis (controls) who were evaluated by laparoscopy. A questionnaire was completed for each patient. Women were also asked about exercise. Exercisers were defined as women who answered 1-2 times a week were referred to as irregular exercisers and ≥3 times a week was defined as regular exercisers. All statistical analyses were carried by SPSS program. Chi-square and t-tests were used to compare the two groups. Logistic regression was done to build a prediction model in endometriosis.
Results
Irregular physical exercise (OR: 2.07; CI: 1.13- 3.81; P=0.01) was associated with a risk of endometriosis. In the logistic regression model, age (P=0.02), level of education (P=0.02), BMI (P<0.001), and exercise (P=0.01) were the main variables that significantly associated with endometriosis.
Conclusion
We find evidence of a beneficial association between regular physical activity and laparoscopically confirmed endometriosis.