P-76: The Effect of Maternal and Paternal Body Mass Index on Live Births after Intracytoplasmic Sperm Injection (ICSI) Cycles
The present study was designed to investigate the effect of couple`s obesity simultaneously on ART outcomes
Materials and methods
This cross-sectional study was performed in Royan institute between September 2012 and January 2014. The recorded data of all patients during this time period were evaluated. The study population was limited to ICSI or IVF/ICSI cycles with autologous oocytes and fresh embryos transfer, which height and weight in both gender recorded. Moreover multilevel logistic regression analysis was used to determine the odds of live birth following ICSI cycles. The analysis was performed according to female and male body mass index (BMI) groups whereas normal–weight patients were considered as reference group. Multilevel logistic regression was performed as couple analyses.
In total, 990 women and their husbands went through 927 treatment ICSI and 63 IVF/ICSI cycles during study period. Among ovulatory women, a significant difference between BMI groups was found, with 60% (95% CI: 0.11-0.83) and 84% (CI: 0.02-0.99) decrease in odds of live birth among overweight and obese, respectively. Among anovulatory women, the association between BMI and live birth presented no clear tendencies. About men, the results presented no significant relationship between BMI and live birth. The results revealed that there is no significant association between couples’ BMI and live birth rate.
Increased female BMI independently and negatively influenced live birth after ICSI treatments, but increased male BMI both independently and combined had no impact on live birth after ICSI treatments.