P-66: There Is No Difference between IVF/ICSI Cycle Outcome in Patients With and without PCOS; A Modified Poisson Regression Model
Polycystic ovary syndrome is a frequent condition in women of reproductive age with prevalence rate of 5-10%. This study purposed to determine the relationship between polycystic ovary syndrome and the outcome of assisted reproductive treatment (ART) cycle in Tehran, Iran.
Materials and methods
In this historical cohort study, 996 infertile women who were referred to Royan Institute (Tehran, Iran) were included in the study between January 2012 and December 2013. Polycystic ovary syndrome as a main variable and other potential confounder variables were gathered. Modified Poisson Regression was used to analyze the data. Stata software, version 13 was used for all statistical analyses.
Unadjusted analysis showed that the risk of failure in polycystic ovary syndrome cases was significantly lower than whom did not have polycystic ovary syndrome (risk ratio: 0.79, 95% CI: 0.66-0.95, P=0.014). After adjusting for the confounder variables, there was no difference between risk of fail in women with and without polycystic ovary syndrome (risk ratio: 0.87, 95% CI: 0.72-1.05, P=0.15). The treatment protocol type, the number of embryo transferred grade A and AB, the number of injected ampoule, and age were the significant predictors of ART cycle outcome.
After adjusting for the potential confounders and by modified Poisson regression model, there was no difference between IVF/ICSI cycle outcome in patients with and without polycystic ovary syndrome.