P-59: The Association between Levels of Vitamin E in Follicular Fluid with The Morphology of Oocytes and The Quality of Embryos in Patients with IVF
According to the global increasing trend of infertility, using assisted reproductive technologies to solve this issue is recommended. It seems that vitamin E is an antioxidant with protective role in the body. Therefore, we aimed to investigate the relation between levels of vitamin E in Follicular fluid with the morphology of oocytes and the quality of embryos in patients with IVF.
Materials and methods
This is a cross-sectional analytical study which was done on oocytes and embryos from 50 women with IVF admitted.Inclusion criteria were 20-45 years of age and Infertility caused by male or female factors. Ten thousand units of hCG were injected and after 36 Hours, they were set under the Follicle suction. the amount of vitamin E was measured and consequently the morphology of oocytes and the quality of embryo were evaluated by inverted optical microscope.
583 oocytes and 275 embryos were examined. No significant relation was observed between age, BMI, duration and cause of infertility with vitamin E (P>0.05). At 0.5-1 mg/ dl level of vitamin E, there were higher MII oocytes in comparison with others (P=0.014). Although, the number of 2PN embryos at 0.5-1 mg/dl level of vitamin E was the highest but this difference was not statistically significant (P=0.872).
According to results, at specific levels of Vitamin E, oocytes morphology and embryos quality have been improved