P-31: Effect of Body Mass Index (BMI ) and The Level of Plasma Concentrations of Biomarkers in Semen and Blood Serum in Infertile Men
The present study aimed to shed light focus on the level of certain hormones such as AMH, FSH, LH, Inhibin B, alpha-glucosidase, and testosterone in the seminal plasma and blood serum to patients inferile men groups (azoosperia, oligospermia and normosperia) as well as calculate the body mass index and find some relationships between these biomarkers and BMI for the same patients.
Materials and methods
When the plasma semen examination and blood serum to 41 Iraqi men infertile (azoospermia (n=18), oligospermia (n=18), and normospermia (n=5)) in Sadr Teaching / Najaf Hospital aboratories of Fertility Center and using the ELISA method as well as the measurement of body mass index for these patients, for the period from 01/11/2014 to 01/02/2015.
The results of the current study showed a significant decrease P<0.05 in all hormonal parameters studied when the two groups azoospermia and oligospermia compared with the control group normosperia. As well as the BMI effect is obvious in these vital signs when examined relations where the current study showed significantly inverse relationship between BMI and FSH, LH, and testosterone and the relationship is a positive but not significantly between BMI and inhibin B, alpha-glycosidase and AMH These patients when compared with group control (normospermia). There was no significant difference in the level of concentration of these hormones in semen and serum except testosterone was significantly higher in semen than in plasma serum.
The present study concluded that BMI has an important impact on the level of concentration of hormones FSH, LH, and testosterone, which plays an important role in spermatogenesis and the emergence of cases of patients Azoospermia and Oligospermia.