Past Issue

Volume 9, Supplement 1, Summer 2015 (Presented at 16th Congress on Reproductive Biomedicine and 10th Royan Nursing and Midwifery Seminar) Pages: 39-39

O-30: The Correlation between Myometrial Thickness and In Vitro Fertilization/ Intracyto- Plasmic Sperm Injection (IVF/ ICSI) Outcomes


Background
O-30: The Correlation between Myometrial Thickness and In Vitro Fertilization/ Intracyto- Plasmic Sperm Injection (IVF/ ICSI) Outcomes
Materials and methods
In this prospective cohort study, 453 infertile women undergoing IVF-ET/ICSI cycles without any obvious pathology of uterine were enrolled. Trans-vaginal ultrasounds were conducted on days 2-4 of the cycle (menstrual phase) preceding ovarian stimulation and the day of human chorionic gonadotropin (hCG) injection for measurement of myometrial thickness in anterior and posterior of uterine. The summation of baseline myometrial thickness in anterior and posterior (anterior-posterior diameter), preceding ovarian stimulation was divided into three following main groups: (A) <25 mm, (B) 25-29.9 mm and (C) ≥30 mm.
Results
The clinical pregnancy and implantation rates were significantly lower in group A as compared to groups B and C (P=0.027 and P=0.006, respectively). The mean of myometrial thickness in anterior and posterior of uterine on the day of injection of hCG decreased significantly compared to the previous ovarian stimulation (P<0.001).
Conclusion
In IVF-ET/ICSI cycles, the baseline myometrial thickness (anterior-posterior diameter) <25 mm is associated with lower implantation and pregnancy rates compared with a myometrial thickness ≥25 mm.