Increasing survival rates in patients who suffer from oncological disease and improvement in reproductive medicine techniques has led to increasing use of different fertility preservation methods. The evidence supporting current and forthcoming options for fertility preservation consisted of two main parts as for female and male. Fertility preservation options for female and male depend on the type of treatment. For instance if the treatment includes cancer surgery , fertility-sparing surgery preserving gonads,preservation of the uterus in females , and use of cryopreservation may also be considered prior to surgery, if the risk of gonadal damage is high. On the other hand, if cytotoxic treatment with high risk of gonadal damage is performed for the patients, then use of cryopreservation methods such as sperm banking for males, freezing of embryos and oocytes for females and gonadal tissue freezing should be considered. Gonadal tissue cryopreservation in some conditions could be utilized in male and women specially in prepubertal and adult patients.It should be emphasized that fertility preservation is not limited to cancer patients. There are some non oncological systemic diseases which are treated with chemotherapy or radiotherapy, such as autoimmune and hematological conditions. In addition, there are other interventions that may impair fertility, such as recurrent ovarian surgery for benign disease , like endometriosis or prophylactic oophorectomy in women with BRCA mutations. Therefore, today fertility preservation is also commonly utilized in non-cancer conditions, increasing the number of females who may benefit from current available and established techniques. In this presentation we will review the current state, approach, and indications of different established as well as experimental methods for fertility preservation.
Materials and methods