-Recurrent pregnancy loss defined as two or more miscarriage before 20 weeks of pregnancy affecting 1-5 % or women in reproductive age .There are many etiologies have been suggested, like Genetic, Immunologic, Thrombophila, Endocrine and Anatomic; but in 50% of cases, the exact etiology remains uncertain. Endometrium acts as biosensor of embryo quality and endometrium itself contribute in embryo implantation and growth. Recently It has been shown that embryo selectivity impaired in the endometrium of patients with recurrent abortion, so poor embryo allowed to be implanted. There are many conflicting results provided from prevailing studies about the effectiveness of current treatment modalities. There are many suggested diagnostic and treatment options selected from recently published papers which will be presented in the lecture.
Materials and methods