The conventional ovarian stimulation protocol aims to provide the maximum number of oocytes for fertilization which is lead to several embryos for selecting to transfer. There are some complications in this case like; OHSS, Multiple gestation, Time consuming, Patients discomfort, High costs, Emotional distress and Reduced implantation rate due to the embryo- endometrial asynchrony. Recently, an increased scientific interest is focused on mild approach for ovarian stimulation in clinical practice. Milder stimulation aims to develop safer and more patient-friendly protocol which is less expensive, less drug use, more physiological and the risk of treatment is highly minimized. On the base of recent systematic reviews and meta- analysis, mild stimulation could be applied for the poor, high and normoresponders which are going to be discussed in detail at Royan Award 2015.
Materials and methods